Cancer

The Role of Genetics in Cancer

Hello again! We've already discussed cancer and its various risk factors. Today, we’ll dive into a more intricate aspect: the role of genetics in cancer. Don’t worry, we’ll break it down in an easy-to-understand way.

Genetics and Cancer

Genes are segments of DNA that carry instructions for every function in our body. Sometimes, these genes can undergo changes or mutations, leading to uncontrolled cell growth, which can ultimately cause cancer.

Inherited and Acquired Mutations

There are two main types of genetic mutations associated with cancer:

Inherited Mutations

Inherited mutations are passed down from parent to child and account for about 5-10% of all cancer cases. Families with a hereditary cancer syndrome may have mutations in specific genes that increase the risk of developing various types of cancer.

Acquired Mutations

Acquired mutations happen throughout a person’s lifetime and are far more common than inherited mutations. They can occur due to external factors such as exposure to radiation, certain chemicals, or simply by chance during normal cell division.

Genetic Testing for Cancer

Genetic testing can help identify mutations that might increase the risk of developing cancer. If you have a family history of cancer, your doctor might recommend undergoing genetic testing to better understand your risk.

Prevention and Hope

While genetics do play a role in cancer development, they don’t dictate everything. Many lifestyle choices can influence your overall risk of cancer. Here are some key prevention tips:

  • Maintain a healthy diet.
  • Stay physically active.
  • Avoid smoking and limit alcohol consumption.

Even if you have a genetic predisposition to cancer, advances in early detection and prevention provide hope. Science is constantly evolving, offering new ways to monitor and reduce risks associated with cancer.

For more information on genetics and cancer, check out the National Cancer Institute and the American Cancer Society.

See you next time!

Sources:

  1. National Cancer Institute. (2023). Genetics and Cancer. Recovered from: https://www.cancer.gov/about-cancer/causes-prevention/genetics/overview-pdq 
  2. American Cancer Society. (2023). Inherited genetic mutations. Recovered from: https://www.cancer.org/cancer/understanding-cancer/genes-and-cancer/gene-changes.html 
  3. Mayo Clinic. (2023). Genetic mutations and cancer. Recovered from: https://www.mayoclinic.org/diseases-conditions/cancer/symptoms-causes/syc-20370588#:~:text=Cancer%20refers%20to%20any%20one,of%20death%20in%20the%20world
  4. Centers of Disease Control and Prevention. (2023). Genetic testing for cancer. Recovered from: https://www.cdc.gov/cancer/genomics/index.htm 

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